A Model for Interphase Chromosomes and Evaluation of Radiation-Induced Aberrations
نویسندگان
چکیده
منابع مشابه
A model for interphase chromosomes and evaluation of radiation-induced aberrations.
We have developed a theoretical model for evaluating radiation-induced chromosomal exchanges by explicitly taking into account interphase (G(0)/G(1)) chromosome structure, nuclear organization of chromosomes, the production of double-strand breaks (DSBs), and the subsequent rejoinings in a faithful or unfaithful manner. Each of the 46 chromosomes for human lymphocytes (40 chromosomes for mouse ...
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We investigated the viscoelastic response of model interphase chromosomes by tracking the three-dimensional motion of hundreds of dispersed Brownian particles of sizes ranging from the thickness of the chromatin fiber up to slightly above the mesh size of the chromatin solution. In agreement with previous computational studies on polymer solutions and melts, we found that the large-time behavio...
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Visualization of interphase chromosomes.
Using a modified Giemsa-banding technique we have observed what appear to be chromosomes during interphase in nuclei from Allium cepa root tips and Chinese hamster cells (CHO line). During telophase through G1 chromosomes progressively uncoil and decondense. During S chromosomes are comparatively decondensed, but some segments have structure similar to chromosomes in G1 and G2. During G2 the ch...
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ژورنال
عنوان ژورنال: Radiation Research
سال: 2002
ISSN: 0033-7587,1938-5404
DOI: 10.1667/0033-7587(2002)158[0568:amfica]2.0.co;2